본문 바로가기 주메뉴 바로가기

Research

Home

Biomimetic chip/actuator

Cytoskeleton actuator

Principle
  • Analyzing cytoskeleton structure with simulation program
Research contents
  • Changing composition of cytoskeleton proteins such as actin filament, myosin, and so on
  • Shrinkage, contraction force and shape vary as composition changes

  • Real Image of actomyosin contraction

  • Simulation model of 3D actomyosin contraction

Cell-like actuator containing cytoskeleton

Principle
  • Understanding and utilizing of contraction dynamics of cytoskeleton structure
Research contents
  • Fabrication of cell-sized actomyosin actuators
  • Analysis of contractile behaviors of actomyosin structures such as contraction speed,
    direction, pattern formation

  • Fabrication of cytoskeleton actuators

  • Cell-sized cytoskeleton actuators

Nose-on-a-chip

Principle
  • Patient-derived nasal cell culture using microfluidic chip: cilia differentiation and mucus secretion
Research contents
  • Biomimetic nasal chip development
  • Observation of tissue thickness increase, cilium differentiation, and mucus secretion as cells grow
  • Patient-derived cells for personalized medicine studies

  • HNEC(Human nasal epithelial cell) cultured on Nose-on-a-Chip

  • Cilia of HNEC(Human nasal epithelial cell)

  • Analysis of various biological data of cells during the culture period

Nasal cilia oscillation

Principle
  • Analysis of beating frequency and movement of nasal cilia
Research contents
  • Movement analysis of differentiated cilia
  • Measurement of cilia beating frequency
  • Tracking beads moving due to cilia

  • Cilia of HNEC

  • Nasal cilia

Flexible actuator

Principle
  • Design and fabrication of flexible actuators consisting of soft materials such as hydrogel and polymer film
Research contents
  • FEM computational modeling of flexible actuators
  • Fabrication and mechanical characterization of flexible actuators

  • Design of flexible actuators

  • Multi-stimuli responsive flexible actuator

맨 위로가기