MECHANOBIOLOGY AND SOFT MATERIALS LAB

Mechanotransduction

Cells are able to produce, sense, and response to mechanical cues. Mechanotransduction refers to the mechanisms by which mechanical cues are converted into biochemical activities. We are specially interested in how mechanotransduction is altered in the state of diseases where the mechanical environments such as stiffness, boundary, and shape change significantly. Results of the studies are applied in understanding causes of diseases, developing new treatments, and constructing biomimetic tissue platform for drug tests.

research5Figure – Aβ1-42 fibril aggregated at
room temperature